Growth patterns of microscopic brain tumors

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Growth patterns of microscopic brain tumors.

Highly malignant brain tumors such as glioblastoma multiforme form complex growth patterns in vitro in which invasive cells organize in tenuous branches. Here, we formulate a chemotaxis model for this sort of growth. A key element controlling the pattern is homotype attraction, i.e., the tendency for invasive cells to follow pathways previously explored. We investigate this in two ways: we show...

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ژورنال

عنوان ژورنال: Physical Review E

سال: 2002

ISSN: 1063-651X,1095-3787

DOI: 10.1103/physreve.66.051901